Today AnyDAC “natively" supports DBMS listed below. “Natively” means:
 | Oracle Database Server v 8.0.3 and higher | OCI |
 | MySQL Server v 3.23 and higher | MySQL API |
 | MS SQL Server v 2000 and higher | ODBC for MSSQL 2000. Native Client for MSSQL 2005 |
 | IBM DB2 Universal Database v 8 and higher | IBM DB2 CLI |
 | Sybase Adaptive Server Anywhere v 8 and higher | Sybase ASA ODBC |
 | MS Access v 2000 and higher | MS Jet ODBC |
 | Advantage Database Server v 8 and higher | ADS ODBC |
| | CodeGear InterBase v 6 and higher | IB API |
 | Firebird v 1.5 and higher | FB API |
And we have successfully played using AnyDAC with IB/FB using dbExpress driver, Postgre SQL using ODBC, Mimer using ODBC, etc.