Use the TADPhysSQLiteDriverLink component to link the SQLite driver to an application. In general it is enough to only include uADPhysSQLite unit into your application uses clause. 

The TADPhysSQLiteDriverLink component may be used to specify SQLite client library to the driver, when the dynamic linking is used. To have an effect all property changes must be performed before first connection through this driver or use the Release method.

TADPhysSQLiteDriverLink = class(TADPhysDriverLink);

Configuring Drivers, Connect to SQLite database, Using SQLite with AnyDAC